The Advantages of RNA Probes over DNA Probes for the Detection of HPV HR in Human Pathology

Recorded On: 10/15/2020

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When setting up and validating a new testing for the lab, several factors must be taken into consideration. Some of which are time management of the pathologists and the technologists. But the greatest considerations are the quality and ease of reading the test and making a correct diagnosis for the patient. When comparing RNA technology against DNA technology, the advantages and disadvantages of both technologies must be evaluated. Which test will produce the highest quality of staining and be able to be render the most optimal diagnosis? What are the advantages of RNA probes and RNAscope™ technology over DNA probes and DNA technology? Which test is most optimal for correct treatment of tumors of the Head and Neck? This lecture will discuss the advantages and disadvantages of both technologies.

CEUs: This histology course is worth 1 continuing education credit. Course is available for 365 days from date of purchase. 


Research Development


Sheron Lear is with CPA Lab in Research Development and Education. She is passionate about histology and IHC are her passion and love. She is currently working with mRNA ISH as well as several new antibodies for use in the IHC lab.  She is a well known presenter and teacher, and she is often teaching the team at CPA and anyone who wants to expand their knowledge in histology and IHC. Troubleshooting issues that arise are another of her interests. With over 57 continuous years in the profession, she still loves new challenges.

Sameer Talwalkar, MD

Hematopathologist and Medical Director


Dr. Talwalkar is the Hematopathologist and Medical Director, of Molecular Diagnostics Norton Healthcare (CPA Lab).  After receiving his medical degree in 2001 he was a research fellow at the Tata Institute of Fundamental Research in Mumbai India, at the USC Keck School of Medicine in Los Angeles, and at the MD Anderson Cancer Center in Houston TX.  He also did a residency at University of Louisville Hospital and fellowship at MD Anderson and the University of Pittsburgh.  


The Advantages of RNA Probes over DNA Probes for the Detection of HPV HR in Human Pathology
Open to view video.
Open to view video. Objectives: We will discuss the advantages and disadvantages of RNA technology. We will discuss the advantages and disadvantages of DNA technology. You will learn to recognize the various staining patterns of both technologies.
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2 Questions
2 Questions Please complete the survey to receive your CEU certificate.
1.00 CEUs credit  |  Certificate available
1.00 CEUs credit  |  Certificate available