IHC Optimization and Validation: Real World Solutions for a Standardized Approach

Recorded On: 09/14/2021


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This presentation will enable participants to fully grasp why optimization and validation are critical to creating a standardized approach to immunohistochemistry (IHC) in the clinical setting. Other presentations focus on meeting accreditation standards; however, a recognisable gap exists between accreditation requirements and the development of a comprehensive understanding of why the standards exist. The presentation will begin with a review of the theory and practicality of optimization, common to all IHC assays. Tools will be given to participants to introduce standardization into their own optimization procedures. Once an insight into the landscape of variability, with over four million possible assay protocols, is established, participants will be led through the validation phase, including the requirements for predictive markers. Again, theory, practice and tools will be shared. Participants are expected to come out of this presentation with the means to standardize the introduction of new IHC assays in their own laboratories.

CEUs: This histology course is worth 1 continuing education credit. Course is available for 365 days from date of purchase.   

Jeremy Johnston, HT(ASCP)QIHC

Mr. Johnston specializes in histology, immunohistochemistry, molecular and lab management. He received his BS in Chemistry from George Fox University and is a member of the National Society of Histotechnology (NSH), American Society for Clinical Pathology (ASCP), Washington State Histology Society (WSHS), California Histology Society (CSH), Texas Society of Histotechnology (TSH), College of American Pathologists (CAP), International Society for IHC and Molecular Morphology (ISIMM). Jeremy is married to Sara and they have three beautiful kids (Sadie, Micah, and Tessa). Jeremy enjoys hanging out with his family and playing soccer in his spare time.

Nadia Gale

Nadia is the Technical Practice Lead for Anatomic Pathology services within Vancouver Coastal Health. Her work involves all of the technical aspects of Anatomic Pathology, however her passion lies within the realm of protein expression and all things immunohistochemistry.

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IHC Optimization and Validation: Real World Solutions for a Standardized Approach
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Open to view video. Learning Objectives: 1)Participants will learn the differences and methods involved in optimizing and validating immunohistochemistry assays in the clinical setting. 2) Participants will understand the importance of the validation requirements for predictive markers. 3) Participants will be given the tools they need to implement standardized optimization and validation procedures in their own laboratories.
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1.00 CEUs credit  |  Certificate available
1.00 CEUs credit  |  Certificate available
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