Fix It or Forget It!!!
Recorded On: 07/15/2020
Poor fixation is a problem that exists in most settings and can be devastating to research, pathology diagnosis, and ultimately, patient care. In the research setting, most of the work relies heavily on IHC and molecular analysis. IHC staining has significantly increased in the clinical setting as well. Without a proper understanding of fixation and how it affects all aspects of histology, we will continue to struggle to provide diagnosable slides. Having a strong understanding of fixative types and when they are best applied to projects will play a major role in achieving the best results. We owe it to patients involved in clinical trials, animals used for testing, and families anxiously awaiting feedback to make sure each sample is collected and fixed for success.
Research Associate II
Ms. Matta is currently a Research Associate II in the Pathology/Histotechnology Laboratory located at the Frederick National Laboratory for Cancer Research (FNLCR) at the National Cancer Institute, Frederick MD. She is a histologist and Assistant Manager of the Histotechnology Lab that supports basic science research and drug development. She is also employed by Trivergent Health at Frederick Memorial Hospital where she works in the histology laboratory. Working in both a research and a clinical setting play an important role in her approach to histology. And, I think anyone who has had a foot in each door, can attest – it is an in valuable perspective.