Acquired EGFR T790M Mutation in NSCLC: Testing in FFPE Tissue

Recorded On: 04/22/2020

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Recent advancements for improving outcomes in NSCLC include immunotherapy treatments developed through genetic testing. EGFR mutations have been identified as a significant cause of poor response in a subset of NSCLC patients. FDA testing methods are now available using formalin-fixed paraffin embedded tissue to identify these mutations, and other genetic aberrations. The EGFR pathway, angiogenesis, tyrosine-kinase inhibitors, and in-vitro testing on FFPE tissue will be discussed.

CEUs: This histology course is worth 1 continuing education credit. Course is available for 365 days from date of purchase.

Jane Ann Wade, HT(ASCP)MLT

Professor, Medical Laboratory Science

  • Ms. Wade is an instructor at West Virginia University, in the Medical Laboratory Science Department where she teaches and coordinates many courses, including those involving Histotechniques.  She is also a presenter at both national and state conferences, and over the years has served on various committees and workgroups such as the NSH Education Committee, the Medical Laboratory Science Admissions Committee, the Pathologists Assistant Admission Committee, and creating trainings for the Tropical Medicine Laboratory.  Prior to her work with the University of West Virginia, Ms. Wade was the Histopathology Technical Manager at Monongalia General Hospital where Managed Histology, Cytology, and Pathology Transcription Quality Assurance and Quality Control; and many other projects. 


Acquired EGFR T790M Mutation in NSCLC: Testing in FFPE Tissue
Open to view video.
Open to view video. Objectives: 1) Discuss the EGFR pathway and EGFR Mutations in Non‐Small‐Cell Lung Cancer (NSCLC); 2) Discuss the significance of FDA approved EGFR T790M mutation testing in FFPE; 3) Review the importance of proper tissue handling for successful molecular testing.
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1.00 CEUs credit  |  Certificate available
1.00 CEUs credit  |  Certificate available